AI Medical Compendium Journal:
RSC advances

Showing 61 to 70 of 132 articles

Discovery of quinolone derivatives as antimycobacterial agents.

RSC advances
Tuberculosis (TB), an infectious disease caused by (), is an important public health issue. Current first-line drugs administered to TB patients have been in use for over 40 years, whereas second-line drugs display strong side effects and poor compl...

Green synthesis and characterization of gold nanoparticles and their application for the rapid detection of glycyrrhizin with immunochromatographic strips.

RSC advances
In this study, a facile and environmentally friendly synthesis process was proposed without regular chemical additives. We successfully synthesized spherical gold nanoparticles (AuNPs) coated with glycyrrhizin (GL) by using GL as both a reductant and...

Effects of different ozone treatments on the storage quality and stability of fresh peeled garlic.

RSC advances
In order to understand their impacts on the preservation of fresh garlic, varying concentrations of ozone gas and different storage temperatures were tested for this experiment. The results demonstrated that freshly peeled garlic was best preserved b...

AuNP array coated substrate for sensitive and homogeneous SERS-immunoassay detection of human immunoglobulin G.

RSC advances
Owing to the high sensitivity, fast responsiveness and high specificity, immunoassays using surface-enhanced Raman scattering (SERS) as the readout signal displayed great potential in disease diagnosis. In this study, we developed a SERS-immunoassay ...

Polydopamine coated hypodermic needles as a microextraction device for the determination of tricyclic antidepressants in oral fluid by direct infusion MS/MS.

RSC advances
In-needle microextraction consists of the confinement of the sorbent, by coating or packing, inside a metallic needle. The size of the needles reduces the eluent requirements providing an efficient preconcentration of the analytes. In this work, hypo...

Ultrasensitive biosensors based on waveguide-coupled long-range surface plasmon resonance (WC-LRSPR) for enhanced fluorescence spectroscopy.

RSC advances
We investigated the coupling phenomenon between plasmonic resonance and waveguide modes through theoretical and experimental parametric analyses on the bimetallic waveguide-coupled long-range surface plasmon resonance (Bi-WCLRSPR) structure. The calc...

Protein detection enabled using functionalised silk-binding peptides on a silk-coated optical fibre.

RSC advances
We present a new coating procedure to prepare optical fibre sensors suitable for use with protein analytes. We demonstrate this through the detection of AlexaFluor-532 tagged streptavidin by its binding to D-biotin that is functionalised onto an opti...

Self-assembly of diclofenac prodrug into nanomicelles for enhancing the anti-inflammatory activity.

RSC advances
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed for the treatment of various types of inflammatory conditions. Diclofenac is a very common NSAID that is utilized to relieve pain and reduce fever and, most importantly, inflammatio...

Development of a fluorescent immunochromatographic assay based on quantum dots for the detection of fleroxacin.

RSC advances
Fleroxacin (FLE) is a broad-spectrum fluoroquinolone antibiotic widely used in animal husbandry, veterinary medicine and aquaculture. Eating animal-derived foods with FLE residues can cause allergies, poisoning or drug resistance. The water-soluble Q...

Enzyme cascade-amplified immunoassay based on the nanobody-alkaline phosphatase fusion and MnO nanosheets for the detection of ochratoxin A in coffee.

RSC advances
Ochratoxin A (OTA) is a common food contaminant with multiple toxicities and thus rapid and accurate detection of OTA is indispensable to minimize the threat of OTA to public health. Herein a novel enzyme cascade-amplified immunoassay (ECAIA) based o...