AI Medical Compendium Journal:
Turkish journal of biology = Turk biyoloji dergisi

Showing 1 to 9 of 9 articles

SUMA: a lightweight machine learning model-powered shared nearest neighbour-based clustering application interface for scRNA-Seq data.

Turkish journal of biology = Turk biyoloji dergisi
BACKGROUND/AIM: Single-cell transcriptomics (scRNA-Seq) explores cellular diversity at the gene expression level. Due to the inherent sparsity and noise in scRNA-Seq data and the uncertainty on the types of sequenced cells, effective clustering and c...

Deep learning in bioinformatics.

Turkish journal of biology = Turk biyoloji dergisi
Deep learning is a powerful machine learning technique that can learn from large amounts of data using multiple layers of artificial neural networks. This paper reviews some applications of deep learning in bioinformatics, a field that deals with ana...

StemnesScoRe: an R package to estimate the stemness of glioma cancer cells at single-cell resolution.

Turkish journal of biology = Turk biyoloji dergisi
BACKGROUND/AIM: Glioblastoma is the most heterogeneous and the most difficult-to-treat type of brain tumor and one of the deadliest among all cancers. The high plasticity of glioma cancer stem cells and the resistance they develop against multiple mo...

Physicochemical differences between camelid single-domain antibodies and mammalian antibodies.

Turkish journal of biology = Turk biyoloji dergisi
BACKGROUND/AIM: In recent years, single-domain antibodies, also known as nanobodies, have emerged as an alternative to full immunoglobulin Gs (IgGs), due to their various advantages, including increased solubility, faster clearance, and cheaper produ...

Comparative evaluation of nano and bulk tin dioxide cytotoxicity on dermal fibroblasts by real-time impedance-based and conventional methods.

Turkish journal of biology = Turk biyoloji dergisi
In this study, the possible cellular effects of tin dioxide (SnO) nanoparticles, together with its bulk form, on mouse dermal fibroblasts (DFs) were revealed using in vitro assays. Particle characterizations were carried out with AFM, Braun-Emmet-Tel...

Evaluation of antiproliferative and protective effects of Eupatorium cannabinum L. extracts.

Turkish journal of biology = Turk biyoloji dergisi
Eupatorium cannabinum L. (Asteraceae) has been used for a long time for medicinal purposes due to its various pharmacological effects and richness in active compounds such as phenolics, sesquiterpenes, pyrrolizidine alkaloids, and polysaccharides. De...

Increased elastic modulus of plasma polymer coatings reinforced with detonation nanodiamond particles improves osteogenic differentiation of mesenchymal stem cells.

Turkish journal of biology = Turk biyoloji dergisi
In the present study we demonstrated that composite PPHMDS/DND coatings with elastic moduli close to those of mature bone tissue (0.2-2.8 GPa) stimulated growth and osteogenic differentiation of human adipose-derived mesenchymal stem cells (hADMSCs)....

Evaluation of the lifespan extension effects of several Turkish medicinal plants in Caenorhabditis elegans.

Turkish journal of biology = Turk biyoloji dergisi
Research on longevity is important to both prolong lifespan and support healthy aging. Natural products are widely being utilized and used as new resources for drug molecules. Caenorhabditis elegans is an advantageous organism for longevity research ...

Antifungal activity of chitinase II against Colletotrichum falcatum Went. causing red rot disease in transgenic sugarcane.

Turkish journal of biology = Turk biyoloji dergisi
We evaluated transgenic lines of sugarcane modified with the barley chitinase class-II gene to create resistance against the red rot causative agent Colletotrichum falcatum Went. Local sugarcane cultivar SP93 was transformed with a 690-bp coding sequ...