AI Medical Compendium Journal:
Turkish journal of pharmaceutical sciences

Showing 1 to 10 of 20 articles

Rapid Stability Indicating HPLC Method for the Analysis of Leflunomide and Its Related Impurities in Bulk Drug and Formulations.

Turkish journal of pharmaceutical sciences
OBJECTIVES: Leflunomide (LFNM) is a drug that belongs to isoxazole derivatives and has immunosuppressive and anti-inflammatory activities. A literature search confirms that there is no method reported for the simultaneous estimation of LFNM and its r...

Antibacterial and Antibiofilm Activities of Ceragenins against Clinical Isolates.

Turkish journal of pharmaceutical sciences
OBJECTIVES: can cause life-threatening infections that are difficult to treat due to its high resistance to antibiotics and its ability to form antibiotic tolerant biofilms. Ceragenins, designed to mimic the activities of antimicrobial peptides, rep...

Flavonoids Isolated from , an Underutilized Vegetable, Exert Monoamine A & B Inhibitory and Anti-inflammatory Effects and Their Structure-activity Relationship.

Turkish journal of pharmaceutical sciences
OBJECTIVES: belongs to family Lamiaceae; it consists of flowering plants and it is also called the mint family. The Yoruba people of southwest Nigeria called it "Oriri" or "Efo oriri". This plant is classified as an underutilized vegetable and littl...

Spectrophotometric Quantification of Anti-inflammatory Drugs by Application of Chromogenic Reagents.

Turkish journal of pharmaceutical sciences
OBJECTIVES: Simple, specific, accurate, precise, sensitive, and cost effective spectrophotometric methods were developed and validated for quantification of the drugs lornoxicam (LOR) and mesalamine (MES) in pure form and in pharmaceutical formulatio...

Intrinsic Stability Study and Forced Degradation Profiling of Olopatadine Hydrochloride by RP-HPLC-DAD-HRMS Method.

Turkish journal of pharmaceutical sciences
OBJECTIVES: Forced degradation determines the intrinsic stability of a molecule by establishing degradation pathways in order to identify the likely degradation products (DPs). The objective of the present research was to establish intrinsic stabilit...

Synthesis and Hypoglycemic and Anti-inflammatory Activity Screening of Novel Substituted 5-[Morpholino(Phenyl)Methyl]-Thiazolidine-2,4-Diones and Their Molecular Docking Studies.

Turkish journal of pharmaceutical sciences
OBJECTIVES: The aim was the synthesis of novel substituted 5-[morpholino(phenyl)methyl]-thiazolidine-2,4-diones and screening for their hypoglycemic activity and anti-inflammatory activity, as well as molecular docking studies to find out active po...

Comparative Assessment of the Methanol Extracts of the Leaf, Stem, and Root Barks of on Lung and Breast Cancer Cell Lines.

Turkish journal of pharmaceutical sciences
OBJECTIVES: Mill. I.M.Johnst. is a medicinal plant widely used in ethnomedicine for the treatment of cancer and other diseases.

The Influence of Piperine on the Radioprotective Effect of Curcumin in Irradiated Human Lymphocytes.

Turkish journal of pharmaceutical sciences
OBJECTIVES: Ionizing radiation (IR) induces DNA damage in normal cells, leading to genotoxicity. The radioprotective effects of co-treatment with curcumin and piperine were investigated against genotoxicity induced by IR in human normal lymphocytes.

Macrophage Nitric Oxide and Interleukin-1 Beta Suppression by Seed.

Turkish journal of pharmaceutical sciences
OBJECTIVES: has long been used in folk medicine to treat diseases including fever, headache, burns, constipation, gut pains, and inflammation. Nitric oxide (NO) and interleukin-1β (IL-1β) play an important role in the pathophysiology of inflammation...

An Study on the Cytotoxicity and Genotoxicity of Silver Sulfide Quantum Dots Coated with Meso-2,3-dimercaptosuccinic Acid.

Turkish journal of pharmaceutical sciences
OBJECTIVES: Silver sulfide (AgS) quantum dots (QDs) are highly promising nanomaterials in bioimaging systems due to their high activities for both imaging and drug/gene delivery. There is insufficient research on the toxicity of AgS QDs coated with m...