AIMC Topic: DNA End-Joining Repair
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Predicting CRISPR/Cas9-Induced Mutations for Precise Genome Editing.
Trends in biotechnology
Sep 13, 2019
SpCas9 creates blunt end cuts in the genome and generates random and unpredictable mutations through error-prone repair systems. However, a growing body of recent evidence points instead to Cas9-induced staggered end generation, nonrandomness of muta...
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