Briefings in bioinformatics
Jan 17, 2022
Artificial intelligence (AI) has been transforming the practice of drug discovery in the past decade. Various AI techniques have been used in many drug discovery applications, such as virtual screening and drug design. In this survey, we first give a...
Briefings in bioinformatics
Jan 17, 2022
Drug-target interaction (DTI) is an important step in drug discovery. Although there are many methods for predicting drug targets, these methods have limitations in using discrete or manual feature representations. In recent years, deep learning meth...
Bioinformatics (Oxford, England)
Jan 12, 2022
MOTIVATION: Identifying drug-target interactions (DTIs) is a crucial step in drug repurposing and drug discovery. Accurately identifying DTIs in silico can significantly shorten development time and reduce costs. Recently, many sequence-based methods...
Current topics in medicinal chemistry
Jan 1, 2022
The role of computational tools in the drug discovery and development process is becoming central, thanks to the possibility to analyze large amounts of data. The high throughput and affordability of current omics technologies, allowing quantitative ...
Current topics in medicinal chemistry
Jan 1, 2022
BACKGROUND: The lengthy and expensive process of developing a novel medicine often takes many years and entails a significant financial burden due to its poor success rate. Furthermore, the processing and analysis of quickly expanding massive data ne...
Current pharmaceutical design
Jan 1, 2022
Due to the heap of data sets available for drug discovery, modern drug discovery has taken the shape of big data. Usage of Artificial intelligence (AI) can help to modify drug discovery based on big data to precised, knowledgeable data. The pharmaceu...
Current pharmaceutical design
Jan 1, 2022
Artificial intelligence is the leading branch of technology and innovation. The utility of artificial intelligence in the field of medicine is also remarkable. From drug discovery and development to introducing products to the market, artificial inte...
Combinatorial chemistry & high throughput screening
Jan 1, 2022
The advancement of computing and technology has invaded all the dimensions of science. Artificial intelligence (AI) is one core branch of Computer Science, which has percolated to all the arenas of science and technology, from core engineering to med...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2022
The use of artificial intelligence methods in drug safety began in the early 2000s with applications such as predicting bacterial mutagenicity and hERG inhibition. The field has been endlessly expanding ever since and the models have become more comp...
Methods in molecular biology (Clifton, N.J.)
Jan 1, 2022
The improvement in the ability of the pharmaceutical industry to predict human pharmacokinetic behavior are attributable to major technological shifts from 1990 to the present day. The opportunity for the application of AI/ML based approaches in the ...