AIMC Topic: Herpesvirus 4, Human

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Exploring genetic and immune cell dynamics in systemic lupus erythematosus patients with Epstein-Barr virus infection via machine learning.

Rheumatology (Oxford, England)
OBJECTIVES: EBV is a widespread virus implicated in various diseases, including SLE. However, the specific genes and pathways altered in SLE patients with EBV infection remain unclear. We aimed to identify key genes and immune cells in SLE patients w...

microT-CNN: an avant-garde deep convolutional neural network unravels functional miRNA targets beyond canonical sites.

Briefings in bioinformatics
microRNAs (miRNAs) are central post-transcriptional gene expression regulators in healthy and diseased states. Despite decades of effort, deciphering miRNA targets remains challenging, leading to an incomplete miRNA interactome and partially elucidat...