AIMC Topic: Receptors, Antigen, T-Cell

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TEINet: a deep learning framework for prediction of TCR-epitope binding specificity.

Briefings in bioinformatics Mar 19, 2023
The adaptive immune response to foreign antigens is initiated by T-cell receptor (TCR) recognition on the antigens. Recent experimental advances have enabled the generation of a large amount of TCR data and their cognate antigenic targets, allowing m...
Epitopes, T-Lymphocyte Deep Learning Receptors, Antigen, T-Cell Protein Binding
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PiTE: TCR-epitope Binding Affinity Prediction Pipeline using Transformer-based Sequence Encoder.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing Jan 1, 2023
Accurate prediction of TCR binding affinity to a target antigen is important for development of immunotherapy strategies. Recent computational methods were built on various deep neural networks and used the evolutionary-based distance matrix BLOSUM t...
Humans Neural Networks, Computer Receptors, Antigen, T-Cell Computational Biology Amino Acids Epitopes
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