Heart disease remains one of the leading causes of mortality globally, resulting in millions of deaths annually and imposing a significant burden on healthcare infrastructure and clinical management systems. This alarming prevalence underscores the c... read more
Exploratory research in clinical and social pharmacy
Dec 16, 2025
BACKGROUND: Due to altered drug clearance, renal impairment necessitates drug dose adjustments to prevent toxicity or therapeutic failure, yet inappropriate dosing persists. The utility of AI tools (e.g., ChatGPT®, DeepSeek®) in supporting renal dose... read more
Soft robotics solutions to unmet clinical needs represent an emergent disruptive technology. However, clear guidelines on the selection of sterilization methods that consider the preservation of essential physical and functional characteristics of su... read more
Experimental and therapeutic medicine
Dec 16, 2025
The mechanisms underlying the pathogenesis of septic cardiomyopathy (SCM) are intricate and incompletely understood. PANoptosis is a novel type of programmed cell death, and in the present study, bioinformatics, machine learning and experimental vali... read more
BACKGROUND: Diagnosing central adrenal insufficiency (CAI) is challenging in patients with inconclusive morning cortisol (4-18 µg/dL). Dynamic tests like the short Synacthen test (SST) are imperfect, necessitating reliable tools to stratify CAI risk ... read more
Scientific foundation models hold great promise for advancing nuclear and particle physics by improving analysis precision and accelerating discovery. Yet, progress in this field is often limited by the lack of openly available large-scale datasets, ... read more
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
Dec 16, 2025
OBJECTIVE: Alzheimer's disease (AD) is strongly associated with aging, yet the interactions remain unclear. This study modeled replicative senescence in patient-derived fibroblasts to compare gene expression between AD dementia and controls across se... read more
Journal of environmental sciences (China)
Dec 16, 2025
Urban-suburban disparities in ozone (O3) pollution have received growing attention due to their implications for environmental equity and public health. However, the underlying drivers of these disparities remain poorly understood, especially the con... read more
American journal of physical medicine & rehabilitation
Dec 15, 2025
OBJECTIVES: Transfers between wheelchairs and beds pose injury risks to users and caregivers, with conventional devices often inefficient and unsafe. The Powered Personal Transfer System-a no-lift solution integrating an electric powered wheelchair a... read more
Despite the profound prevalence and fracture risk of osteoporosis, access to the gold standard DXA scans remains limited, especially in rural communities. Rho is an artificial intelligence software that can identify individuals at risk of low BMD and... read more
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