Artificial Intelligence Medical Compendium

Colloidal drug aggregates are amorphous nanoparticles formed by the self-assembly of hydrophobic small molecule drugs. They can be leveraged as drug-rich nanoparticle formulations for drug delivery. However, it is difficult to predict which drugs wil... read more 

It is well known that porcine reproductive and respiratory syndrome (PRRS) decreases herd productivity and leads to economic loss, and it is believed that biosecurity practices are effective for the control and eradication of PRRS. This study aimed t... read more 

Glucagon-like peptide-1 (GLP-1), a pivotal incretin hormone modulating glycemic homeostasis, has emerged as a clinically validated target for the treatment of type 2 diabetes and obesity. In this study, we present a comprehensive AI-integrated drug d... read more 

Proteins and enzymes are fundamental elements for the correct regulation of cell metabolism and their dysregulation or malfunction can lead to the onset of several pathologies. Altered enzymes can participate in tumour formation and progression, but ... read more 

Accurate identification of carcinogenic hazards is essential for public health protection, yet traditional animal-based assays are time-consuming, expensive, and ethically challenging. Many existing quantitative structure-activity relationship (QSAR)... read more 

OBJECTIVES: To evaluate the effect of image type on the performance of a deep learning classification model for decision-making in orthodontic treatment planning, and to investigate the clinical applicability of artificial intelligence in determining... read more 

BACKGROUND: Steroid hormone profiles in affective disorders suggest hypothalamic-pituitary-adrenal (HPA) axis dysregulation and may reveal novel therapeutic targets. However, most existing studies focus narrowly on glucocorticoids. This study aims to... read more 

BACKGROUND: Diagnosis of prostate cancer in the PSA gray zone (4-10 ng/mL) and PI-RADS 3 cases remains challenging. Although multiparametric MRI (mpMRI) is widely used, its diagnostic accuracy is limited by inter-reader variability and the lack of in... read more 

Balancing metabolic pathways is critical for engineering microbial platforms to efficiently and robustly synthesize value-added bioproducts. In the oleaginous yeast Yarrowia lipolytica engineered for β-carotene production, lipid synthesis supports ca... read more 

BACKGROUND: Thymic epithelial tumors (TETs) are rare malignancies that pose significant diagnostic challenges due to their heterogeneous histological patterns and substantial interobserver variability in classification. Despite standardized World Hea... read more