Clinical biomechanics (Bristol, Avon)
Dec 11, 2025
BACKGROUND: Patellofemoral pain (PFP) in active women is associated with gait adaptations. The Movement Deviation Profile (MDP) summarises deviations in multi-segment kinematic deviation, but it is unclear how the magnitude of deviation relates to pa... read more
Precision medicine has transformed healthcare by tailoring treatment plans to an individual's genetic profile, in contrast to standardized therapies. Patient-derived tumoroids facilitate cancer research, while extracellular vesicles (EVs) provide ins... read more
PURPOSE: An artificial intelligence (AI) system for detecting interstitial lung abnormalities (ILA) was previously developed but requires external validation. This study aimed to examine the robustness across different populations and investigate ass... read more
Stroke remains a leading cause of mortality and long-term disability worldwide, where rapid diagnosis and timely intervention are critical for improving outcomes. Neurovascular imaging modalities, including magnetic resonance angiography, computed to... read more
BACKGROUND: Several omics methods have been successfully used in hypertension prediction. However, the predictive ability of various multiomics data has not been compared in the same study sample, and it is unknown whether they provide additional pre... read more
BACKGROUND: Hypertension is a major contributor to cardiovascular morbidity and mortality. Its heterogeneity complicates risk stratification. Unsupervised machine learning can uncover risk profiles and refine preventative strategies. This study appli... read more
INTRODUCTION: Artificial intelligence (AI) is revolutionizing healthcare by enhancing diagnostics, optimizing treatment plans, and improving patient outcomes through data analysis and predictive modeling. Within the field of reproductive endocrinolog... read more
BACKGROUND: Lymph node metastasis is important for the management and surgical procedures of patients with colorectal cancer. Preoperative identification of D3 metastasis could help evaluate the necessity of D3 lymphadenectomy. No adequate noninvasiv... read more
Given the well-established structural and functional changes in the aging brain, it is widely assumed that cognitive aging is primarily driven by robust group-level differences between young and older adults. However, our individual-level EEG functio... read more
Adeno-associated virus (AAV) vectors are excellent gene-delivery carriers in gene therapy; however, improperly packaged capsids produced during manufacturing can reduce potency and raise safety concerns. We introduce a machine-learning-assisted, low-... read more
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