Development of machine learning models predicting mortality using routinely collected observational health data from 0-59 months old children admitted to an intensive care unit in Bangladesh: critical role of biochemistry and haematology data.

Journal: BMJ paediatrics open
Published Date:

Abstract

INTRODUCTION: Treatment in the intensive care unit (ICU) generates complex data where machine learning (ML) modelling could be beneficial. Using routine hospital data, we evaluated the ability of multiple ML models to predict inpatient mortality in a paediatric population in a low/middle-income country.

Authors

  • Subhasish Das
    Nutrition and Clinical Services Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
  • Lauren Erdman
    Genetics and Genome Biology Program, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Daniella Brals
    Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands.
  • Bartlomiej Boczek
    Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands.
  • S M Tafsir Hasan
    Nutrition Research Division, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
  • Paraskevi Massara
    The Center for Computational Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada.
  • Md Ashraful Alam
    The University of Queensland Poche Centre for Indigenous Health, Saint Lucia, Queensland, Australia.
  • Shah Mohammad Fahim
    Nutrition and Clinical Services Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
  • Mustafa Mahfuz
    Nutrition and Clinical Services Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
  • Mark Hoogendoorn
    Vrije Universiteit Amsterdam, Department of Computer Science, De Boelelaan 1081, Amsterdam 1081 HV, The Netherlands.
  • Teun Zuiderent-Jerak
    Athena Institute, Faculty of Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
  • Robert H J Bandsma
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
  • Tahmeed Ahmed
    Nutrition and Clinical Services Division, International Center for Diarrheal Disease and Research, Bangladesh (icddr,b), Dhaka, Bangladesh.
  • Wieger Voskuijl
    Department of Global Health, Amsterdam Institute for Global Health and Development, Amsterdam, Netherlands.