Risk factors and development of machine learning diagnostic models for lateral lymph node metastasis in rectal cancer: multicentre study.

Journal: BJS open
PMID:

Abstract

BACKGROUND: The diagnostic criteria for lateral lymph node metastasis in rectal cancer have not been established. This research aimed to investigate the risk factors for lateral lymph node metastasis and develop machine learning models combining these risk factors to improve the diagnostic performance of standard imaging.

Authors

  • Shunsuke Kasai
    Division of Colon and Rectal Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
  • Akio Shiomi
  • Hideyuki Shimizu
    Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Monami Aoba
    Department of AI Systems Medicine, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan.
  • Yusuke Kinugasa
  • Takuya Miura
    Department of Biological Sciences, Graduate School of Science, Osaka University, Toyonaka, Japan.
  • Kay Uehara
    Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School Hospital, Tokyo, Japan.
  • Jun Watanabe
    Department of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Japan.
  • Kazushige Kawai
    Department of Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
  • Yoichi Ajioka
    Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.