Deep learning application of vertebral compression fracture detection using mask R-CNN.

Journal: Scientific reports
Published Date:

Abstract

Vertebral compression fractures (VCFs) of the thoracolumbar spine are commonly caused by osteoporosis or result from traumatic events. Early diagnosis of vertebral compression fractures can prevent further damage to patients. When assessing these fractures, plain radiographs are used as the primary diagnostic modality. In this study, we developed a deep learning based fracture detection model that could be used as a tool for primary care in the orthopedic department. We constructed a VCF dataset using 487 lateral radiographs, which included 598 fractures in the L1-T11 vertebra. For detecting VCFs, Mask R-CNN model was trained and optimized, and was compared to three other popular models on instance segmentation, Cascade Mask R-CNN, YOLOACT, and YOLOv5. With Mask R-CNN we achieved highest mean average precision score of 0.58, and were able to locate each fracture pixel-wise. In addition, the model showed high overall sensitivity, specificity, and accuracy, indicating that it detected fractures accurately and without misdiagnosis. Our model can be a potential tool for detecting VCFs from a simple radiograph and assisting doctors in making appropriate decisions in initial diagnosis.

Authors

  • Seungyoon Paik
    School of Industrial and Management Engineering, Korea University, Anam-ro 145, Seongbuk-gu, Seoul, 02841, South Korea.
  • Jiwon Park
    Department of Transportation and Logistics Engineering, Hanyang University Erica Campus, Ansan 15588, Korea.
  • Jae Young Hong
    Department of Orthopaedic Surgery, Korea University Ansan Hospital, 123, Jeokgeum-ro, Danwon-gu, Ansan, Gyeonggi-do, South Korea.
  • Sung Won Han
    Department of Industrial and Management Engineering, Korea University, Seoul 02841, the Republic of Korea.