Proximal junctional failure (PJF) is a significant mechanical complication following corrective surgery for adult spinal deformity (ASD), often resulting in structural failure at the uppermost instrumented vertebra and necessitating revision surgery....
Numerical variations and transitional anatomy in the human vertebral column represent a significant yet understudied aspect of skeletal development with potential effects on multiple physiological systems. Utilising UK Biobank data, we integrated gen...
Journal of neuroengineering and rehabilitation
Oct 22, 2025
The restoration of standing and walking after spinal cord injury (SCI) remains a top priority for individuals with paraplegia. Despite significant advancements in neuromodulation techniques, challenges such as limited selectivity and inconsistent out...
Lumbar spinal stenosis involves pathological narrowing of the spinal canal, whereas disc degeneration refers to the progressive deterioration of intervertebral disc structure and function. Interspinous process devices (ISPs) are commonly used to mana...
Advancing our understanding of spinal biomechanics through Finite Element Analysis (FEA) is essential for clinical decision-making and biomechanical research. Traditional FEA workflows are hindered by manual segmentation and meshing, introducing inco...
Magnetic resonance imaging (MRI) serves as the clinical gold standard for diagnosing lumbar disc herniation (LDH). This multicenter study was to develop and clinically validate a deep learning (DL) model utilizing axial T2-weighted lumbar MRI sequenc...
To develop an algorithmic approach for predicting surgical site infections (SSIs) in patients undergoing lumbar laminectomy and discectomy for adult degenerative spinal disease (DSD) by incorporating ensembled stacking into state-of-the-art (SOTA) au...
With an increasing aging population, the prevalence of chronic comorbidities is on the rise. The potential relationship between obstructive sleep apnea (OSA) and osteoporosis has garnered significant attention. Most studies examining the association ...
BACKGROUND: Lumbar disc degeneration (LDD) displays considerable heterogeneity in terms of clinical features and pathological changes. However, researchers have not clearly determined whether the transcriptome variations in LDD could be used to ident...
BMC medical informatics and decision making
Jul 28, 2025
BACKGROUND: Lumbar spinal stenosis is one of the most common surgery-requiring conditions of the spine in the aged population. As elderly patients often present with multiple comorbidities and limited physiological reserve, individualized risk assess...
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