Predicting the 28-day prognosis of acute-on-chronic liver failure patients based on machine learning.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
PMID:

Abstract

BACKGROUND: We aimed to establish a prognostic predictive model based on machine learning (ML) methods to predict the 28-day mortality of acute-on-chronic liver failure (ACLF) patients, and to evaluate treatment effectiveness.

Authors

  • Shaotian Qiu
    The School of Medicine, Nankai University, Tianjin 300071, China; Department of Gastroenterology and Hepatology, Tianjin Union Medical Center Affiliated to Nankai University, Tianjin 300121, China.
  • Yumeng Zhao
    The School of Medicine, Nankai University, Tianjin 300071, China.
  • Jiaxuan Hu
    The School of Medicine, Nankai University, Tianjin 300071, China; Department of Gastroenterology and Hepatology, Tianjin Union Medical Center Affiliated to Nankai University, Tianjin 300121, China.
  • Qian Zhang
    The Neonatal Intensive Care Unit, Peking Union Medical College Hospital, Peking, China.
  • Lewei Wang
    Department of Gastroenterology and Hepatology, Tianjin Union Medical Center of Tianjin Medical University, Tianjin 300121, China.
  • Rui Chen
    College of Food Science and Engineering, Northwest A&F University, Yangling 712100, Shanxi, China.
  • Yingying Cao
    Department of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China.
  • Fang Liu
    The First Clinical Medical College of Gannan Medical University, Ganzhou 341000, Jiangxi Province, China.
  • Caiyan Zhao
    Department of Infectious Disease, the Third Hospital of Hebei Medical University, Shijiazhuang 050051, China.
  • Liaoyun Zhang
    Department of Infection Disease, First Hospital of Shanxi Medical University, Taiyuan 030001, China.
  • Wanhua Ren
    Infectious Department of Shandong First Medical University Affiliated Shandong Provincial Hospital, Jinan 250021, China.
  • Shaojie Xin
    Liver Failure Treatment and Research Center, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China.
  • Yu Chen
    State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China.
  • Zhongping Duan
    Liver Disease Center (Difficult & Complicated Liver Diseases and Artificial Liver Center), Beijing You'an Hospital Affiliated to Capital Medical University, Beijing 100069, China.
  • Tao Han
    Food Science and Engineering College, Beijing University of Agriculture, Beijing, 102206, China.