Bifurcation detection in intravascular optical coherence tomography using vision transformer based deep learning.

Journal: Physics in medicine and biology
Published Date:

Abstract

. Bifurcation detection in intravascular optical coherence tomography (IVOCT) images plays a significant role in guiding optimal revascularization strategies for percutaneous coronary intervention (PCI). We propose a bifurcation detection method using vision transformer (ViT) based deep learning in IVOCT.. Instead of relying on lumen segmentation, the proposed method identifies the bifurcation image using a ViT-based classification model and then estimate bifurcation ostium points by a ViT-based landmark detection model.. By processing 8640 clinical images, the Accuracy and F1-score of bifurcation identification by the proposed ViT-based model are 2.54% and 16.08% higher than that of traditional non-deep learning methods, are similar to the best performance of convolutional neural networks (CNNs) based methods, respectively. The ostium distance error of the ViT-based model is 0.305 mm, which is reduced 68.5% compared with the traditional non-deep learning method and reduced 24.81% compared with the best performance of CNNs based methods. The results also show that the proposed ViT-based method achieves the highest success detection rate are 11.3% and 29.2% higher than the non-deep learning method, and 4.6% and 2.5% higher than the best performance of CNNs based methods when the distance section is 0.1 and 0.2 mm, respectively.. The proposed ViT-based method enhances the performance of bifurcation detection of IVOCT images, which maintains a high correlation and consistency between the automatic detection results and the expert manual results. It is of great significance in guiding the selection of PCI treatment strategies.

Authors

  • Rongyang Zhu
    School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, People's Republic of China.
  • Qingrui Li
    School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, People's Republic of China.
  • Zhenyang Ding
    School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, People's Republic of China.
  • Kun Liu
    Department of Anesthesiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China.
  • Qiutong Lin
    School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, People's Republic of China.
  • Yin Yu
    School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, People's Republic of China.
  • Yuanyao Li
    Tianjin Institute of Metrological Supervision and Testing, Tianjin 300192, People's Republic of China.
  • Shanshan Zhou
    From the Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Rd, Chaoyang District, Beijing 100029, China (Z.Z., Y.G., N.Z., H.W., R.W., L.X.); School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou, China (W.Z., Z.G., H.Z.); Keya Medical Company, Shenzhen, China (X.H.); Department of Cardiology, Chinese PLA General Hospital, Beijing, China (S.Z.); Department of Radiology, The First Hospital of China Medical University, Shenyang, China (X.D.); Cardiovascular Research Centre, Royal Brompton Hospital, London, UK (G.Y.); National Heart and Lung Institute, Imperial College London, London, UK (G.Y.); and Department of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, Calif (K.N.).
  • Hao Kuang
    Nanjing Forssmann Medical Technology Co., Nanjing, Jiangsu 210093, People's Republic of China.
  • Junfeng Jiang
    School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, People's Republic of China.
  • Tiegen Liu
    School of Precision Instruments and Opto-Electronics Engineering, Tianjin University, Tianjin 300072, People's Republic of China.