Reconstructing Cancellous Bone From Down-Sampled Optical-Resolution Photoacoustic Microscopy Images With Deep Learning.

Journal: Ultrasound in medicine & biology
PMID:

Abstract

OBJECTIVE: Bone diseases deteriorate the microstructure of bone tissue. Optical-resolution photoacoustic microscopy (OR-PAM) enables high spatial resolution of imaging bone tissues. However, the spatiotemporal trade-off limits the application of OR-PAM. The purpose of this study was to improve the quality of OR-PAM images without sacrificing temporal resolution.

Authors

  • Jingxian Wang
    Human Phenome Institute, Fudan University, Shanghai, China.
  • Boyi Li
    Academy for Engineering and Technology, Fudan University, Shanghai, China.
  • Tianhua Zhou
    Key Laboratory of Space Laser Communication and Detection Technology, Shanghai Institute of Optics and Fine Mechanics, Chinses Academy of Sciences, Shanghai 201800, China.
  • Chengcheng Liu
    State Key Laboratory of Oral Diseases, Department of Periodontics, National Clinical Research Center for Oral Diseases, West China School & Hospital of Stomatology, Sichuan University, Chengdu, China.
  • Mengyang Lu
  • Wenting Gu
    Academy for Engineering and Technology, Fudan University, Shanghai, China.
  • Xin Liu
    Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences, Weifang, Shandong, China.
  • Dean Ta