Using Machine Learning and miRNA for the Diagnosis of Esophageal Cancer.

Journal: The journal of applied laboratory medicine
Published Date:

Abstract

BACKGROUND: Esophageal cancer (EC) remains a global health challenge, often diagnosed at advanced stages, leading to high mortality rates. Current diagnostic tools for EC are limited in their efficacy. This study aims to harness the potential of microRNAs (miRNAs) as novel, noninvasive diagnostic biomarkers for EC. Our objective was to determine the diagnostic accuracy of miRNAs, particularly in distinguishing miRNAs associated with EC from control miRNAs.

Authors

  • Vishnu A Aravind
    REHS program, San Diego Supercomputer Center, UC San Diego, San Diego, CA, United States.
  • Valentina L Kouznetsova
    San Diego Supercomputer Center, University of California at San Diego, La Jolla, CA 92093, USA.
  • Santosh Kesari
    Pacific Neuroscience Institute, Santa Monica, CA 90404, USA.
  • Igor F Tsigelny
    San Diego Supercomputer Center, University of California at San Diego, La Jolla, CA 92093, USA.