What the trained eye cannot see: Quantitative kinematics and machine learning detect movement deficits in early-stage Parkinson's disease from videos.

Journal: Parkinsonism & related disorders
Published Date:

Abstract

BACKGROUND: Evaluation of disease severity in Parkinson's disease (PD) relies on motor symptoms quantification. However, during early-stage PD, these symptoms are subtle and difficult to quantify by experts, which might result in delayed diagnosis and suboptimal disease management.

Authors

  • Diego L Guarin
    Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Cambridge.
  • Joshua K Wong
  • Nikolaus R McFarland
    Fixel Institute for Neurological Disease, College of Medicine, University of Florida, Gainesville, FL.
  • Adolfo Ramirez-Zamora
  • David E Vaillancourt
    Laboratory for Rehabilitation Neuroscience, Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL.