Artificial Intelligence-Based Digital Biomarkers for Type 2 Diabetes: A Review.

Journal: The Canadian journal of cardiology
Published Date:

Abstract

Type 2 diabetes mellitus (T2DM), a complex metabolic disorder that burdens the health care system, requires early detection and treatment. Recent strides in digital health technologies, coupled with artificial intelligence (AI), may have the potential to revolutionize T2DM screening, diagnosis of complications, and management through the development of digital biomarkers. This review provides an overview of the potential applications of AI-driven biomarkers in the context of screening, diagnosing complications, and managing patients with T2DM. The benefits of using multisensor devices to develop digital biomarkers are discussed. The summary of these findings and patterns between model architecture and sensor type are presented. In addition, we highlight the pivotal role of AI techniques in clinical intervention and implementation, encompassing clinical decision support systems, telemedicine interventions, and population health initiatives. Challenges such as data privacy, algorithm interpretability, and regulatory considerations are also highlighted, alongside future research directions to explore the use of AI-driven digital biomarkers in T2DM screening and management.

Authors

  • Mariam Jabara
    Centre for Outcome Research & Evaluation, McGill University Health Centre, Montréal, Québec, Canada; Division of Experimental Medicine, Faculty of Medicine and Health Science, McGill University, Montréal, Québec, Canada.
  • Orhun Kose
    Division of Experimental Medicine, Faculty of Medicine and Health Science, McGill University, Montréal, Québec, Canada; DREAM-CV Lab, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
  • George Perlman
    Division of Experimental Medicine, Faculty of Medicine and Health Science, McGill University, Montréal, Québec, Canada; DREAM-CV Lab, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
  • Simon Corcos
    HOP-Child Technologies, Sherbrooke, Québec, Canada.
  • Marc-Antoine Pelletier
    HOP-Child Technologies, Sherbrooke, Québec, Canada.
  • Elite Possik
    DREAM-CV Lab, Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.
  • Michael Tsoukas
    Centre for Outcome Research & Evaluation, McGill University Health Centre, Montréal, Québec, Canada; Department of Endocrinology, McGill University Health Centre, Montréal, Québec, Canada.
  • Abhinav Sharma
    Department of Biological Sciences and Bioengineering (BSBE), IIT, Kanpur, India.