Diabetic kidney disease (DKD) progression is not well understood. Using high-throughput proteomics, biostatistical, pathway and machine learning tools, we examine the urinary Complement proteome in two prospective cohorts with type 1 or 2 diabetes an...
Exhaled gas detection offers a safe, convenient, and non-invasive clinical diagnostic method for preventing the progression of diabetes to complications. In this study, gas chromatography-mass spectrometry (GC-MS) analysis and statistical methods wer...
A growing body of literature supports the association between ambient particulate pollution and the risk of type 2 diabetes (T2DM). Both issues are particularly relevant in Italy. This study investigates the relationship between T2DM and exposure to ...
Universal differential equations (UDEs) are an emerging approach in biomedical systems biology, integrating physiology-driven mathematical models with machine learning for data-driven model discovery in areas where knowledge of the underlying physiol...
The accurate prediction of blood glucose is critical for the effective management of diabetes. Modern continuous glucose monitoring (CGM) technology enables real-time acquisition of interstitial glucose concentrations, which can be calibrated against...
The prevalence of type 2 diabetes mellitus (T2DM) in Korea has risen in recent years, yet many cases remain undiagnosed. Advanced artificial intelligence models using multi-modal data have shown promise in disease prediction, but two major challenges...
BACKGROUND: Pancreatic cellular heterogeneity is fundamental to systemic metabolic regulation, yet its pathological remodeling in diabetes remains poorly characterized.
The increasing prevalence of type 2 diabetes (T2D) is a significant health concern worldwide. Effective and personalized treatment strategies are essential for improving patient outcomes and reducing healthcare costs. Machine learning (ML) has the po...
BACKGROUND: Epicardial adipose tissue (EAT) is associated with cardiometabolic risk in type 2 diabetes (T2D), but its spatial distribution and structural alterations remain understudied. We aim to develop a shape-aware, AI-based method for automated ...
Elevated postprandial glucose levels present a global epidemic and a major challenge in type-2 diabetes (T2D) management. A key barrier to developing effective dietary interventions for T2D management is the wide inter-individual variation in glycemi...
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