Sex and population differences in the cardiometabolic continuum: a machine learning study using the UK Biobank and ELSA-Brasil cohorts.

Journal: BMC public health
Published Date: Aug 6, 2024

Abstract

BACKGROUND: The temporal relationships across cardiometabolic diseases (CMDs) were recently conceptualized as the cardiometabolic continuum (CMC), sequence of cardiovascular events that stem from gene-environmental interactions, unhealthy lifestyle influences, and metabolic diseases such as diabetes, and hypertension. While the physiological pathways linking metabolic and cardiovascular diseases have been investigated, the study of the sex and population differences in the CMC have still not been described.

Authors

  • Daniela Polessa Paula
    National School of Statistical Sciences, Brazilian Institute of Geography and Statistics, Rio de Janeiro, Brazil. danielapopaula@gmail.com.
  • Marina Camacho
    Departament de Matemàtiques i Informàtica, Universitat de Barcelona, Barcelona, Spain.
  • Odaleia Barbosa
    Institute of Nutrition, University of the Rio de Janeiro State, Rio de Janeiro, Brazil.
  • Larissa Marques
    Coordination of Information and Communication (CINCO - PEIC), Oswaldo Cruz Foundation, Rio de Janeiro, Rio de Janeiro, Brazil.
  • Rosane Harter Griep
    Health and Environmental Education Laboratory, Oswaldo Cruz Institute (IOC), Rio de Janeiro, RJ, Brazil.
  • Maria Jesus Mendes da Fonseca
    National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
  • Sandhi Barreto
    Postgraduate Program in Public Health, School of Medicine & Clinical Hospital, Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Karim Lekadir
    Information and Communication Technologies Department, Universitat Pompeu Fabra, Barcelona, Spain.

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