AIMC Topic: Sex Factors
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Physiological serum uric acid concentrations correlate with arterial stiffness in a sex-dependent manner.
BMC medicine
Jul 1, 2025
BACKGROUND: In humans, uric acid is a product of purine metabolism that impacts the vascular system. In addition to effects on arterial vascular tone, associations between serum uric acid concentrations-even in the physiological range-and arterial hy...
AI-based CT assessment of 3117 vertebrae reveals significant sex-specific vertebral height differences.
Scientific reports
Jul 1, 2025
Predicting vertebral height is complex due to individual factors. AI-based medical imaging analysis offers new opportunities for vertebral assessment. Thereby, these novel methods may contribute to sex-adapted nomograms and vertebral height predictio...
Moral judgments in online discourse are not biased by gender.
Scientific reports
Jul 1, 2025
The interaction between social norms and gender roles prescribes gender-specific behaviors that influence moral judgments. While previous work has demonstrated the existence of gender-bias in judgments, these studies are mainly based on controlled ex...
A supervised machine learning approach with feature selection for sex-specific biomarker prediction.
NPJ systems biology and applications
Jul 1, 2025
Biomarkers are crucial in aiding in disease diagnosis, prognosis, and treatment selection. Machine learning (ML) has emerged as an effective tool for identifying novel biomarkers and enhancing predictive modelling. However, sex-based bias in ML algor...
Improving a data mining based diagnostic support tool for rare diseases on the example of M. Fabry: Gender differences need to be taken into account.
PloS one
Jun 30, 2025
BACKGROUND: Rare diseases often present with a variety of clinical symptoms and therefore are challenging to diagnose. Fabry disease is an x-linked rare metabolic disorder. The severity of symptoms is usually different in men and women. Since therape...
Uncovering nonlinear patterns in time-sensitive prehospital breathing emergencies: an exploratory machine learning study.
BMC medical informatics and decision making
Jun 3, 2025
BACKGROUND: Timely prehospital care is crucial for patients presenting with high-risk time-sensitive (HRTS) conditions. However, the interplay between response time and demographic factors in patients with breathing problems remains insufficiently un...
Gasdermin D drives the systemic storm and mortality after trauma with hemorrhage to a greater degree in biological females than males.
Science translational medicine
May 28, 2025
Severe injury accompanied by hemorrhagic shock triggers an early release of cell constituents into the circulation, referred to as the systemic storm. The systemic storm drives the systemic inflammatory response and is associated with increased morta...
Examining the empathy levels of medical students using CHAID analysis.
BMC medical education
May 19, 2025
BACKGROUND: Empathy is a key factor in the medical field as it strengthens doctor-patient relationships, enhances communication, and leads to improved patient outcomes. This study aims to investigate the empathy levels of medical students, providing ...
Gender-specific sarcopenia screening in hemodialysis: insights from lower limb strength and physiological indicators.
BMC nephrology
May 19, 2025
OBJECTIVE: Maintenance hemodialysis (MHD) patients often suffer from sarcopenia, affecting lower limb muscle strength and increasing the risk of falls and mortality. This study aims to develop an auxiliary screening model for sarcopenia in MHD patien...
[Cluster predictors of trajectories of leisure-time physical activity intensity in men and women from ELSA-Brasil].
Cadernos de saude publica
May 19, 2025
The maintenance of physical activity over time is a challenge for public health. Predictors of different physical activity intensities have not been sufficiently analyzed. This study aimed to identify clusters of trajectories of physical activity int...
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