3D-printed microrobots for biomedical applications.

Journal: Biomaterials science
PMID:

Abstract

Microrobots, which can perform tasks in difficult-to-reach parts of the human body under their own or external power supply, are potential tools for biomedical applications, such as drug delivery, microsurgery, imaging and monitoring, tissue engineering, and sensors and actuators. Compared with traditional fabrication methods for microrobots, recent improvements in 3D printers enable them to print high-precision microrobots, breaking through the limitations of traditional micromanufacturing technologies that require high skills for operators and greatly shortening the design-to-production cycle. Here, this review first introduces typical 3D printing technologies used in microrobot manufacturing. Then, the structures of microrobots with different functions and application scenarios are discussed. Next, we summarize the materials (body materials, propulsion materials and intelligent materials) used in 3D microrobot manufacturing to complete body construction and realize biomedical applications (, drug delivery, imaging and monitoring). Finally, the challenges and future prospects of 3D printed microrobots in biomedical applications are discussed in terms of materials, manufacturing and advancement.

Authors

  • Kun Wei
    a State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education , Guizhou University , Guiyang , PR China.
  • Chenlong Tang
    School of Biomedical Engineering, 3D-Printing and Tissue Engineering Center, Anhui Medical University, Hefei, 230032, China. yangrunhuai@ahmu.edu.cn.
  • Hui Ma
    National Centre for Sensor Research and School of Biotechnology, Dublin City University, Collins Avenue, D09 Y5N0, 9 Dublin, Ireland.
  • Xingmiao Fang
    School of Biomedical Engineering and the 3D-Printing and Tissue Engineering Center (3DPTEC), Anhui Medical University, Hefei 230032, China. yangrunhuai@ahmu.edu.cn.
  • Runhuai Yang
    School of Biomedical Engineering, Anhui Medical University, Hefei 230032, P.R.China.