Prediction model of in-hospital cardiac arrest using machine learning in the early phase of hospitalization.

Journal: The Kaohsiung journal of medical sciences
Published Date:

Abstract

In hospitals, the deterioration of a patient's condition leading to death is often preceded by physiological abnormalities in the hours to days beforehand. Several risk-scoring systems have been developed to identify patients at risk of major adverse events; however, such systems often exhibit low sensitivity and specificity. To identify the risk factors associated with in-hospital cardiac arrest (IHCA), we conducted a retrospective cohort study at a tertiary medical center in Taiwan. Four machine learning algorithms were employed to identify the factors most predictive of IHCA. The support vector machine model was discovered to be the most effective at predicting IHCA. The ten most critical physiological parameters at 8 h prior to the event were pulse rate, age, white blood cell count, lymphocyte count, body temperature, body mass index, systolic and diastolic blood pressure, platelet count, and use of central nervous system-active medication. Using these parameters, we can enhance early warning and rapid response systems in our hospital, potentially reducing the incidence of IHCA in clinical practice.

Authors

  • Wei-Tsung Wu
    Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
  • Chew-Teng Kor
    Big Data Center, Changhua Christian Hospital, Changhua City, Taiwan.
  • Ming-Chung Chou
    Center for Big Data Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Hui-Min Hsieh
    Center for Big Data Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Wan-Chih Huang
    Center for Big Data Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Wei-Ling Huang
    Center for quality management and patient safety, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
  • Shu-Yen Lin
    Center for Big Data Research, Kaohsiung Medical University, Kaohsiung, Taiwan.
  • Ming-Ru Chen
    Big Data Center, Changhua Christian Hospital, Changhua City, Taiwan.
  • Tsung-Hsien Lin
    Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital; ; Department of Internal Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.