Semi-supervised recognition for artificial intelligence assisted pathology image diagnosis.

Journal: Scientific reports
Published Date:

Abstract

The analysis and interpretation of cytopathological images are crucial in modern medical diagnostics. However, manually locating and identifying relevant cells from the vast amount of image data can be a daunting task. This challenge is particularly pronounced in developing countries where there may be a shortage of medical expertise to handle such tasks. The challenge of acquiring large amounts of high-quality labelled data remains, many researchers have begun to use semi-supervised learning methods to learn from unlabeled data. Although current semi-supervised learning models partially solve the issue of limited labelled data, they are inefficient in exploiting unlabeled samples. To address this, we introduce a new AI-assisted semi-supervised scheme, the Reliable-Unlabeled Semi-Supervised Segmentation (RU3S) model. This model integrates the ResUNet-SE-ASPP-Attention (RSAA) model, which includes the Squeeze-and-Excitation (SE) network, Atrous Spatial Pyramid Pooling (ASPP) structure, Attention module, and ResUNet architecture. Our model leverages unlabeled data effectively, improving accuracy significantly. A novel confidence filtering strategy is introduced to make better use of unlabeled samples, addressing the scarcity of labelled data. Experimental results show a 2.0% improvement in mIoU accuracy over the current state-of-the-art semi-supervised segmentation model ST, demonstrating our approach's effectiveness in solving this medical problem.

Authors

  • Yao Pan
    Department of Radiology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, Zhejiang, China (Y.P., R.-S.Y.).
  • Fangfang Gou
    School of Computer Science and Engineering, Central South University, Changsha 410083, China.
  • Chunwen Xiao
    The Second People's Hospital of Huaihua, Huaihua, 418000, China.
  • Jun Liu
    Department of Radiology, Second Xiangya Hospital, Changsha, Hunan, China.
  • Jing Zhou