Enhancing Organizing Pneumonia Diagnosis: A Novel Super-token Transformer Approach for Masson Body Segmentation.

Journal: In vivo (Athens, Greece)
Published Date:

Abstract

BACKGROUND/AIM: In this study, we introduce an innovative deep-learning model architecture aimed at enhancing the accuracy of detecting and classifying organizing pneumonia (OP), a condition characterized by the presence of Masson bodies within the alveolar spaces due to lung injury. The variable morphology of Masson bodies and their resemblance to adjacent pulmonary structures pose significant diagnostic challenges, necessitating a model capable of discerning subtle textural and structural differences. Our model incorporates a novel architecture that integrates advancements in three key areas: Semantic segmentation, texture analysis, and structural feature recognition.

Authors

  • Jing-Tong Fu
    Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.
  • Yi-Siang Tan
    Department of Electrical Engineering, National Cheng Kung University, Tainan, Taiwan, R.O.C.
  • Pau-Choo Chung
  • Yu Hsin Tsai
    Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.
  • Pin-Kuei Fu
    Division of Clinical Research, Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.
  • Chih Jung Chen
    Department of Pathology and Laboratory Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, R.O.C.; cjchen1016@vghtc.gov.tw.