Developing a prediction model for cognitive impairment in older adults following critical illness.

Journal: BMC geriatrics
PMID: 39614152

Abstract

BACKGROUND: New or worsening cognitive impairment or dementia is common in older adults following an episode of critical illness, and screening post-discharge is recommended for those at increased risk. There is a need for prediction models of post-ICU cognitive impairment to guide delivery of screening and support resources to those in greatest need. We sought to develop and internally validate a machine learning model for new cognitive impairment or dementia in older adults after critical illness using electronic health record (EHR) data.

Authors

  • Ashley E Eisner
    Department of Internal Medicine, Section on Pulmonology, Critical Care, Allergy & Immunologic Diseases, Wake Forest University School of Medicine, 2 Watlington Hall, 1 Medical Center Boulevard, Winston-Salem, NC, 27157, USA.
  • Lauren Witek
    Informatics and Analytics, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, USA.
  • Nicholas M Pajewski
    Department of Biostatistics and Data Science, Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
  • Stephanie P Taylor
    Division of Hospital Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
  • Richa Bundy
    Informatics and Analytics, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, USA.
  • Jeff D Williamson
    Section on Geriatric Medicine and Gerontology, Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
  • Byron C Jaeger
    Kirklin Institute for Research in Surgical Outcomes, University of Alabama at Birmingham.
  • Jessica A Palakshappa
    Department of Internal Medicine, Section on Pulmonology, Critical Care, Allergy & Immunologic Diseases, Wake Forest University School of Medicine, 2 Watlington Hall, 1 Medical Center Boulevard, Winston-Salem, NC, 27157, USA. jpalaksh@wakehealth.edu.

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