BACKGROUND: Several potentially modifiable risk factors are associated with subjective cognitive decline (SCD). However, developmental patterns of these risk factors have not been used before to forecast later SCD. Practical tools for the prevention ...
Studies in health technology and informatics
40357607
Cognitive Reserve (CR) refers to the brain's ability to compensate for brain damage or age-related changes, which can explain why some individuals show greater cognitive resilience to brain pathology despite damage or age-related changes. Understandi...
BACKGROUND AND OBJECTIVES: Cortical lesions in multiple sclerosis (MS) severely affect cognition, but their longitudinal evolution and impact on specific cognitive functions remain understudied. This study investigates the evolution of function-speci...
American journal of Alzheimer's disease and other dementias
40322901
To improve the identification of cognitive impairment by distinguishing normal cognition (NC), mild cognitive impairment (MCI), and Alzheimer's disease (AD). A recursive partitioning tree model was developed using ARMADA data and the NIH Toolbox, a...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
40232896
Detecting Alzheimer's disease (AD) in its earliest stages, particularly during an onset of Mild Cognitive Impairment (MCI), remains challenging due to the overlap of initial symptoms with normal aging processes. Given that no cure exists and current ...
BACKGROUND: Cognitive impairment, indicative of Alzheimer disease and other forms of dementia, significantly deteriorates the quality of life of older adult populations and imposes considerable burdens on families and health care systems worldwide. T...
Dual-task composed of gait or stepping tasks combined with cognitive tasks has been well-established as valuable tools for detecting neurocognitive disorders such as mild cognitive impairment and early-stage Alzheimer's disease. We previously develop...
White matter hyperintensities (WMH) are neuroimaging markers linked to an elevated risk of cognitive decline. WMH severity is typically assessed via visual rating scales and through volumetric segmentation. While visual rating scales are commonly use...
The heterogeneity of cerebral small vessel disease (CSVD) with mild cognitive impairment (MCI) presents a challenge for diagnosis and classification. This study aims to propose a multimodal magnetic resonance imaging (MRI)-based machine learning fram...
In the context of lifestyle changes, stress and other environmental factors have resulted in the sudden hike in dementia globally. This necessitates investigations with respect to every horizon of the due cause for it; further on, the diagnosis and t...