HKA-Net: clinically-adapted deep learning for automated measurement of hip-knee-ankle angle on lower limb radiography for knee osteoarthritis assessment.

Journal: Journal of orthopaedic surgery and research
PMID:

Abstract

BACKGROUND: Accurate measurement of the hip-knee-ankle (HKA) angle is essential for informed clinical decision-making in the management of knee osteoarthritis (OA). Knee OA is commonly associated with varus deformity, where the alignment of the knee shifts medially, leading to increased stress and deterioration of the medial compartment. The HKA angle, which quantifies this alignment, is a critical indicator of the severity of varus deformity and helps guide treatment strategies, including corrective surgeries. Current manual methods are labor-intensive, time-consuming, and prone to inter-observer variability. Developing an automated model for HKA angle measurement is challenging due to the elaborate process of generating handcrafted anatomical landmarks, which is more labor-intensive than the actual measurement. This study aims to develop a ResNet-based deep learning model that predicts the HKA angle without requiring explicit anatomical landmark annotations and to assess its accuracy and efficiency compared to conventional manual methods.

Authors

  • Young-Tak Kim
  • Beom-Su Han
    Department of Orthopedic Surgery, Seoul Medical Center, 156 Shinnae-Ro, Jungnang-Gu, Seoul, 02053, Republic of Korea.
  • Jung Bin Kim
    Department of Neurology, Korea University Anam Hospital, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea. Electronic address: kjbin80@korea.ac.kr.
  • Jason K Sa
    Department of Biomedical Sciences, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea; Department of Biomedical Informatics, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
  • Je Hyeong Hong
    Department of Electronic Engineering, Hanyang University, 222, Wangsimni-ro, Seongdong-gu, Seoul, 04763, Republic of Korea.
  • Yunsik Son
    Department of Computer Engineering, Dongguk University, Seoul, South Korea.
  • Jae-Ho Han
    Department of Pathology, Ajou University School of Medicine, 206 Worldcup-ro, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16499, Republic of Korea.
  • Synho Do
    Department of Radiology, Massachusetts General Hospital, Boston, MA, USA. sdo@mgh.harvard.edu.
  • Ji Seon Chae
    Department of Anesthesiology and Pain Medicine, College of Medicine, Ewha Womans University, 260 Gonghang-Daero, Gangseo-Gu, Seoul, 07804, Republic of Korea.
  • Jung-Kwon Bae
    Department of Orthopedic Surgery, Seoul Medical Center, 156 Shinnae-Ro, Jungnang-Gu, Seoul, 02053, Republic of Korea. roundnfirm@hanmail.net.