AIMC Topic: Osteoarthritis, Knee

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Distribution of interscan measurement error in AI-based 3D MRI analysis of knee cartilage thickness in osteoarthritis.

PloS one Aug 7, 2025
PURPOSE: A novel AI-based 3D analysis system was developed to automatically extract bone and cartilage from MRI data and provide average cartilage thickness. This study aimed to analyze the interscan measurement error of knee cartilage thickness in o...
Artificial Intelligence Female Aged Humans Magnetic Resonance Imaging Knee Joint Osteoarthritis, Knee Cartilage, Articular Male Middle Aged Imaging, Three-Dimensional
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Applying binary mixed model to predict knee osteoarthritis pain.

PloS one Jul 15, 2025
Data used to understand knee osteoarthritis (KOA) often involves knee-level, rather than person-level information. Failure to account for the correlation between joints within a person may lead to inaccurate inferences. The aim of this study was to d...
Male Middle Aged Pain Measurement Knee Joint Pain Osteoarthritis, Knee Algorithms Female Aged Humans Machine Learning
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Identification of MEG3 and MAPK3 as potential therapeutic targets for osteoarthritis through multiomics integration and machine learning.

Scientific reports Jul 2, 2025
Knee osteoarthritis (KOA) is a prevalent degenerative joint disorder, yet its underlying molecular mechanisms remain puzzling. This study aimed to uncover the genes with a causal relationship to KOA using Mendelian randomization (MR), transcriptomic ...
Mitogen-Activated Protein Kinase 3 Genome-Wide Association Study ROC Curve Multiomics Humans RNA, Long Noncoding Mendelian Randomization Analysis Machine Learning Osteoarthritis, Knee Gene Expression Profiling Quantitative Trait Loci
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Deep learning based classification of tibio-femoral knee osteoarthritis from lateral view knee joint X-ray images.

Scientific reports Jul 1, 2025
Design an effective deep learning-driven method to locate and classify the tibio-femoral knee joint space width (JSW) with respect to both anterior-posterior (AP) and lateral views. Compare the results and see how successfully a deep learning approac...
Radiography Knee Joint Humans Deep Learning Tibia Femur Osteoarthritis, Knee
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The Role of Artificial Intelligence Large Language Models in Personalized Rehabilitation Programs for Knee Osteoarthritis: An Observational Study.

Journal of medical systems Jun 3, 2025
BACKGROUND: Large language models (LLMs) can contribute to treatment options and outcomes by assisting physiotherapists for conditions like osteoarthritis.
Humans Artificial Intelligence Physical Therapy Modalities Precision Medicine Large Language Models Physical Therapists Male Female Middle Aged Aged Osteoarthritis, Knee Cross-Sectional Studies
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OA-HybridCNN (OHC): An advanced deep learning fusion model for enhanced diagnostic accuracy in knee osteoarthritis imaging.

PloS one May 7, 2025
Knee osteoarthritis (KOA) is a leading cause of disability globally. Early and accurate diagnosis is paramount in preventing its progression and improving patients' quality of life. However, the inconsistency in radiologists' expertise and the onset ...
Deep Learning Humans Magnetic Resonance Imaging Female Osteoarthritis, Knee Male
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Machine learning analysis of FOSL2 and RHoBTB1 as central immunological regulators in knee osteoarthritis synovium.

The Journal of international medical research Apr 27, 2025
BackgroundKnee osteoarthritis is a debilitating disease with a complex pathogenesis. Synovitis, which refers to inflammation of the synovial membrane surrounding the joint, is believed to play an important role in the development and progression of k...
Osteoarthritis, Knee Fos-Related Antigen-2 Humans Synovial Membrane Machine Learning Gene Expression Profiling Disease Models, Animal Animals Gene Regulatory Networks Gene Expression Regulation Mice
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Prediction of coronal alignment in robotic-assisted total knee arthroplasty with artificial intelligence.

The Knee Apr 25, 2025
INTRODUCTION: Robotic-assisted technologies provide the ability to avoid soft tissue release by utilizing more accurate bony cuts during total knee arthroplasty (TKA). However, the ideal limb alignment is not yet established. The aim of this study wa...
Retrospective Studies Female Aged Humans Neural Networks, Computer Artificial Intelligence Knee Joint Arthroplasty, Replacement, Knee Osteoarthritis, Knee Male Middle Aged Robotic Surgical Procedures
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Evaluating artificial intelligence performance in medical image analysis: Sensitivity, specificity, accuracy, and precision of ChatGPT-4o on Kellgren-Lawrence grading of knee X-ray radiographs.

The Knee Apr 23, 2025
BACKGROUND: Recent advancements in artificial intelligence, including ChatGPT, have enabled its application in medical image analysis.This study aimed to evaluate the sensitivity and specificity of ChatGPT in assessing knee osteoarthritis (KOA) radio...
Humans Knee Joint Osteoarthritis, Knee Sensitivity and Specificity Male Middle Aged ROC Curve Generative Artificial Intelligence Reproducibility of Results Artificial Intelligence Radiography Aged Retrospective Studies Radiographic Image Interpretation, Computer-Assisted Adult Female
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Accuracy of machine learning in identifying candidates for total knee arthroplasty (TKA) surgery: a systematic review and meta-analysis.

European journal of medical research Apr 22, 2025
BACKGROUND: The application of machine learning (ML) in predicting the requirement for total knee arthroplasty (TKA) at knee osteoarthritis (KOA) patients has been acknowledged. Nonetheless, the variables employed in the development of ML models are ...
Humans Osteoarthritis, Knee Machine Learning Patient Selection Arthroplasty, Replacement, Knee
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