Generalizable Magnetic Resonance Imaging-based Nasopharyngeal Carcinoma Delineation: Bridging Gaps Across Multiple Centers and Raters With Active Learning.

Journal: International journal of radiation oncology, biology, physics
PMID:

Abstract

PURPOSE: To develop a deep learning method exploiting active learning and source-free domain adaptation for gross tumor volume delineation in nasopharyngeal carcinoma (NPC), addressing the variability and inaccuracy when deploying segmentation models in multicenter and multirater settings.

Authors

  • Xiangde Luo
    School of Mechanical and Electrical Engineering, University of Electronic Science and Technology of China, Chengdu, China.
  • Hongqiu Wang
    School of Information and Communication Engineering, University of Electronic Science and Technology of China, Chengdu, China.
  • Jinfeng Xu
    Department of Ultrasound, The Second Clinical Medical College,Jinan University, Guangdong, China.
  • Lu Li
    State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Yue Zhao
    The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China.
  • Yuan He
    Department of Vascular and Endovascular Surgery, Chinese PLA General Hospital, Beijing, PR China. Electronic address: heyuan@301hospital.com.cn.
  • Hui Huang
    Department of Biobank, The Sixth Affiliated People's Hospital of Dalian Medical University, Dalian, Liaoning, China.
  • Jianghong Xiao
    Department of Radiation Oncology, Cancer Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
  • Tao Song
    Department of Cleft Lip and Palate, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing.
  • Shichuan Zhang
    Department of Radiation Oncology, Sichuan Cancer Hospital and Institute, University of Electronic Science and Technology of China, Chengdu, China.
  • Shaoting Zhang
  • Guotai Wang
    Wellcome / EPSRC Centre for Interventional and Surgical Sciences (WEISS), University College London, UK.
  • Wenjun Liao
    Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.