BACKGROUND: Nasopharyngeal carcinoma (NPC) exhibits unique histopathological characteristics compared to other head and neck cancers. The prognosis of NPC patients after intensity-modulated radiation therapy (IMRT) has not been fully studied, and the...
Radiotherapy resistance in nasopharyngeal carcinoma (NPC) is a major cause of recurrence and metastasis. Identifying radiotherapy-related biomarkers is crucial for improving patient survival outcomes. This study developed the nasopharyngeal carcinoma...
ObjectiveThe prediction of early response in locally advanced nasopharyngeal carcinoma (LA-NPC) after concurrent chemoradiotherapy (CCRT) is important for determining the need for timely consolidation therapy. We developed a radiomic analysis of mult...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Apr 8, 2025
BACKGROUND AND PURPOSE: To establish predictive models for radiation-induced hypoglossal neuropathy (RIHN) in patients with nasopharyngeal carcinoma (NPC) after intensity-modulated radiotherapy (IMRT).
BACKGROUND: Previous knowledge-based planning studies have demonstrated the feasibility of predicting three-dimensional photon dose distributions and subsequently generating treatment plans. The steepness of dose fall-off represents a critical metric...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Mar 27, 2025
PURPOSE: This study aims to develop an artificial intelligence model to predict severe radiation-induced oral mucositis (RIOM) in patients with locally advanced nasopharyngeal carcinoma (LA-NPC) and verify the risk factors associated with severe RIOM...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 24, 2025
BACKGROUND: To investigate the feasibility of detecting local recurrent nasopharyngeal carcinoma (rNPC) using unenhanced magnetic resonance images (MRI) and optimize a layered management strategy for follow-up with a deep learning model.
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Mar 13, 2025
Accurate segmentation of the tumor regions of nasopharyngeal carcinoma (NPC) is of significant importance for radiotherapy of NPC. However, the precision of existing automatic segmentation methods for NPC remains inadequate, primarily manifested in t...
BACKGROUND: Ras-GTPase-activating protein (GAP)-binding protein 1 (G3BP1) emerges as a pivotal oncogenic gene across various malignancies, notably including nasopharyngeal carcinoma (NPC). The use of automated image analysis tools for immunohistochem...
The present study analyzed the impact of age on the causes of death (CODs) in patients with nasopharyngeal carcinoma (NPC) undergoing chemoradiotherapy (CRT) using machine learning approaches. A total of 2841 patients (1037 classified as older, ≥ 60 ...
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