A Machine Learning-Based Approach for the Prediction of Anticoagulant Activity of Hypericum perforatum L. and Evaluation of Compound Activity.

Journal: Phytochemical analysis : PCA
PMID: 39551532

Abstract

INTRODUCTION: Hypericum perforatum L. (HPL) is extensively researched domestically and internationally as a medicinal plant. However, no reports of studies related to the anticoagulant activity of HPL have been retrieved. The specific bioactive components are unknown.

Authors

  • Zhiyong Zhang
  • Wennan Nie
    College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China.
  • Yijing Zhang
  • Mulan He
    College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China.
  • Cunhao Li
    College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
  • Shule Zhang
    College of Pharmaceutical Engineering of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, China.
  • Wenlong Li
    Institute of Clinical Pharmacology, Qilu Hospital, Shandong University, Jinan, China.

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