Deep Learning Unravels Differences Between Kinematic and Kinetic Gait Cycle Time Series from Two Control Samples of Healthy Children Assessed in Two Different Gait Laboratories.

Journal: Sensors (Basel, Switzerland)
PMID:

Abstract

We investigate the application of deep learning in comparing gait cycle time series from two groups of healthy children, each assessed in different gait laboratories. Both laboratories used similar gait analysis protocols with minimal differences in data collection. Utilizing a ResNet-based deep learning model, we successfully identified the source laboratory of each dataset, achieving a high classification accuracy across multiple gait parameters. To address the inter-laboratory differences, we explored various pre-processing methods and time series properties that may have been detected by the algorithm. We found that the standardization of the time series values was a successful approach to decrease the ability of the model to distinguish between the two centers. Our findings also reveal that differences in the power spectra and autocorrelation structures of the datasets play a significant role in the model performance. Our study emphasizes the importance of standardized protocols and robust data pre-processing to enhance the transferability of machine learning models across clinical settings, particularly for deep learning approaches.

Authors

  • Alfonso de Gorostegui
    PhD Program in Neuroscience, Universidad Autonoma de Madrid-Cajal Institute, 28029 Madrid, Spain.
  • Damien Kiernan
    Movement Analysis Laboratory, Central Remedial Clinic, Clontarf, D03 R973 Dublin, Ireland.
  • Juan-Andrés Martín-Gonzalo
    Escuela Universitaria de Fisioterapia de la ONCE, Universidad Autónoma de Madrid, 28034 Madrid, Spain.
  • Javier López-López
    Department of Rehabilitation, Hospital Universitario Infanta Sofía, Fundación para la Investigación e Innovación Biomédica del Hospital Universitario Infanta Sofía y Hospital del Henares, San Sebastián de los Reyes, 28702 Madrid, Spain.
  • Irene Pulido-Valdeolivas
    Department of Anatomy, Histology & Neuroscience, School of Medicine, Universidad Autónoma de Madrid (UAM), 28029 Madrid, Spain.
  • Estrella Rausell
    Department of Anatomy, Histology & Neuroscience, School of Medicine, Universidad Autónoma de Madrid (UAM), 28029 Madrid, Spain.
  • Massimiliano Zanin
    Centro de Tecnología Biomédica, Campus de Montegancedo, Universidad Politecnica de Madrid, Pozuelo de Alarcon, 28223, Madrid, Spain.
  • David Gómez-Andrés
    Child Neurology Unit. Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.