Multi-scale multi-object semi-supervised consistency learning for ultrasound image segmentation.

Journal: Neural networks : the official journal of the International Neural Network Society
Published Date:

Abstract

Manual annotation of ultrasound images relies on expert knowledge and requires significant time and financial resources. Semi-supervised learning (SSL) exploits large amounts of unlabeled data to improve model performance under limited labeled data. However, it faces two challenges: fusion of contextual information at multiple scales and bias of spatial information between multiple objects. We propose a consistency learning-based multi-scale multi-object (MSMO) semi-supervised framework for ultrasound image segmentation. MSMO addresses these challenges by employing a contextual-aware encoder coupled with a multi-object semantic calibration and fusion decoder. First, the encoder extracts multi-scale multi-objects context-aware features, and introduces attention module to refine the feature map and enhance channel information interaction. Then, the decoder uses HConvLSTM to calibrate the output features of the current object by using the hidden state of the previous object, and recursively fuses multi-object semantics at different scales. Finally, MSMO further reduces variations among multiple decoders in different perturbations through consistency constraints, thereby producing consistent predictions for highly uncertain areas. Extensive experiments show that proposed MSMO outperforms the SSL baseline on four benchmark datasets, whether for single-object or multi-object ultrasound image segmentation. MSMO significantly reduces the burden of manual analysis of ultrasound images and holds great potential as a clinical tool. The source code is accessible to the public at: https://github.com/lol88/MSMO.

Authors

  • Saidi Guo
    Cooperative Innovation Center of Internet Healthcare, Zhengzhou University, Zhengzhou 450001, China.
  • Zhaoshan Liu
    School of Economics and Management, Taishan University, Taian 271000, Shandong, China.
  • Ziduo Yang
    Artificial Intelligence Medical Center, School of Intelligent Systems Engineering, Sun Yat-sen University, Shenzhen 510275, China.
  • Chau Hung Lee
    Department of Radiology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. Electronic address: chau_hung_lee@ttsh.com.sg.
  • Qiujie Lv
    School of Intelligent Systems Engineering, Sun Yat-sen University, Shenzhen, 510275, China.
  • Lei Shen
    Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China.