Long-chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients.

Journal: Dermatologic therapy
PMID:

Abstract

Aging well has become the new target of preventative medicine, and aesthetic dermatology can contribute to this request. The polynucleotide (PN) containing products not only fill the space, but improve tissue regeneration, resulting in more natural tissue regeneration. Five Korean women received four times injections of long-chain PN filler in two-week intervals for skin rejuvenation. About 0.05 mL of material was injected in 40 points of one-side cheek. The pore and skin thickness were markedly improved in the patients in their 30s, whereas skin tone, melanin, wrinkles, and sagging were noticeably improved for patients in their 40s. There are no serious side effects. In conclusion, intradermal long-chain PN filler injection seems to be an effective and safe treatment for skin rejuvenation.

Authors

  • Kui Young Park
    Departments of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
  • Joon Seok
    Departments of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
  • Nark Kyoung Rho
    Leaders Aesthetic Laser and Cosmetic Surgery Center, Seoul, Korea.
  • Beom Joon Kim
    Departments of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.
  • Myeung Nam Kim
    Departments of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.