AIMC Topic: Skin

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3D organotypic skin models recapitulate autoantibody-driven pemphigus pathomechanisms and targeted therapeutic response.

Science advances
Advanced three-dimensional (3D) tissue models that recapitulate autoimmune disease progression can enable mechanistic studies and accelerate the development of targeted therapies with reduced reliance on systemic immunosuppression. Here, we present a...

A neuromorphic robotic electronic skin with active pain and injury perception.

Proceedings of the National Academy of Sciences of the United States of America
Humanoid robots with advanced sensory capabilities are increasingly demanded for empathetic, close-contact interactions with humans. Electronic skin (E-skin) is a key enabling technology for such tactile perception. However, current E-skins are limit...

Skin-Integrated Soft Wearable XR Interfaces for Seamless and Realistic User Experience.

Chemical reviews
Extended reality (XR) is an emerging field that connects the physical and digital worlds, enabling communication that transcends time and space. Commercial XR devices have been developed to support such experiences, but they are limited to specific s...

Microorganisms, Microbial Metabolites and Precision Nutrition: Targeting the Gut-Skin Axis for Immune Microenvironment Remodeling in Atopic Dermatitis.

Clinical reviews in allergy & immunology
Atopic dermatitis (AD), characterized by skin barrier dysfunction and microbiota dysbiosis, is closely linked to immune microenvironment imbalance. Growing evidence highlights the crucial role of microorganisms and their metabolites in immune regulat...

AttenUNeT X with iterative feedback mechanisms for robust deep learning skin lesion segmentation.

Scientific reports
Accurate skin lesion segmentation is critical for improving early diagnosis of skin cancer. In this study, we propose AttenUNeT X, a novel extension of the U-Net architecture that integrates three key enhancements: (i) a feedback mechanism within dec...

Progress and Prospects of Transdermal Treatment of Allergic Skin Diseases with Natural Drugs based on Nanotechnology.

AAPS PharmSciTech
Allergic skin disease conditions represent a significant global health challenge, with conventional therapies frequently associated with local dermal irritation and systemic adverse effects. Nanotechnology-enabled transdermal drug delivery platforms ...

Improve deep learning-based reconstruction of optical coherence tomography angiography by siamese U-Net.

Biomedical physics & engineering express
Optical coherence tomography angiography (OCTA), as a functional imaging based on OCT, has found successful medical applications. OCTA produces vasculature imaging using blood flow motion as an intrinsic contrast agent. To date, the prevailing OCTA a...

A deep learning-based dual-branch framework for automated skin lesion segmentation and classification via dermoscopic Images.

Scientific reports
Early skin disease detection significantly improves patient survival rates, yet limited access to dermatological expertise creates an urgent need for automated diagnostic systems. In this paper, we develop a dual-branch deep learning framework that s...

Improved non-invasive detection of sleep stages when combining skin sympathetic nerve activity and heart rate variability analysis with AI.

Scientific reports
Sleep is a cyclic physiological process that goes into different stages, and every stage has its' importance in the construction or recovery of physiological function. Sleep scoring is performed from polysomnography recordings which requires signals ...

Deep Learning-Aided Noninvasive Monitoring of Skin Tissue Temperature Distribution and Blood Perfusion Rate Based on Fractal Conformal Sensors.

ACS sensors
Skin thermophysical properties are key for health assessment with real-time monitoring enabling early detection of skin-related issues. A polydimethylsiloxane-encapsulated Peano fractal conformal sensor is fabricated by flexible printed circuit techn...