AI techniques have facilitated the understanding of epitranscriptome distribution.

Journal: Cell genomics
PMID:

Abstract

N-methyladenosine (m6A), the most prevalent internal mRNA modification in higher eukaryotes, plays diverse roles in cellular regulation. By incorporating both sequence- and genome-derived features, Fan et al. designed a novel Transformer-BiGRU framework that achieves superior performance in computational m6A identification, thus demonstrating the potential of AI in genomic studies.

Authors

  • Daiyun Huang
    Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, PR China. daiyun.huang@liverpool.ac.uk.
  • Jia Meng
    Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu Province, China.
  • Kunqi Chen
    Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu 215123, China.