Artificial intelligence-aided data mining of medical records for cancer detection and screening.

Journal: The Lancet. Oncology
Published Date:

Abstract

The application of artificial intelligence methods to electronic patient records paves the way for large-scale analysis of multimodal data. Such population-wide data describing deep phenotypes composed of thousands of features are now being leveraged to create data-driven algorithms, which in turn has led to improved methods for early cancer detection and screening. Remaining challenges include establishment of infrastructures for prospective testing of such methods, ways to assess biases given the data, and gathering of sufficiently large and diverse datasets that reflect disease heterogeneities across populations. This Review provides an overview of artificial intelligence methods designed to detect cancer early, including key aspects of concern (eg, the problem of data drift-when the underlying health-care data change over time), ethical aspects, and discrepancies between access to cancer screening in high-income countries versus low-income and middle-income countries.

Authors

  • Amalie Dahl Haue
    Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Copenhagen University Hospital Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Jessica Xin Hjaltelin
    Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Peter Christoffer Holm
    Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Davide Placido
    NNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.
  • S Ren Brunak
    Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Copenhagen University Hospital Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. Electronic address: soren.brunak@cpr.ku.dk.