AIMC Topic: Early Detection of Cancer

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AI-assisted cervical cytology precancerous screening for high-risk population in resource-limited regions using a compact microscope.

Nature communications
Insufficient coverage of cervical cytology screening in resource-limited areas remains a major bottleneck for women's health, as traditional centralized methods require significant investment and many qualified pathologists. Using consumer-grade elec...

Deep learning model for early acute lymphoblastic leukemia detection using microscopic images.

Scientific reports
Cancer of bone marrow is classified as Acute Lymphoblastic Leukemia (ALL), an abnormal growth of lymphoid progenitor cells. It affects both children and adults and is the most predominant form of infantile cancer. Currently, there has been significan...

Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer.

eLife
Pancreatic cancer (PC) is a highly aggressive malignancy in humans, where early diagnosis significantly improves patient outcomes. However, effective methods for accurate and early detection remain limited. In this multiethnic study involving human s...

Socioeconomic impact of artificial intelligence-driven point-of-care testing devices for liquid biopsy in the OncoCheck system.

Cancer metastasis reviews
Cancer disparities in low- and middle-income countries (LMICs) persist because of socioeconomic inequalities and limited access to screening infrastructure, which requires equitable diagnostic solutions. As researchers, we need to develop interventio...

Non-invasive breath testing to detect colorectal cancer: protocol for a multicentre, case-control development and validation study (COBRA2 study).

BMC cancer
BACKGROUND: Colorectal cancer (CRC) is the fourth most common cancer in the United Kingdom. The five-year survival rate from CRC is only 10% when discovered at a late stage, but can exceed 90% if diagnosed early. Symptoms related to CRC can be non-sp...

Multiple Tumor-related autoantibodies test enhances CT-based deep learning performance in diagnosing lung cancer with diameters < 70 mm: a prospective study in China.

BMC pulmonary medicine
BACKGROUND: Deep learning (DL) demonstrates high sensitivity but low specificity in lung cancer (LC) detection during CT screening, and the seven Tumor-associated antigens autoantibodies (7-TAAbs), known for its high specificity in LC, was employed t...

Harnessing infrared thermography and multi-convolutional neural networks for early breast cancer detection.

Scientific reports
Breast cancer is a relatively common carcinoma among women worldwide and remains a considerable public health concern. Consequently, the prompt identification of cancer is crucial, as research indicates that 96% of cancers are treatable if diagnosed ...

Accuracy and acceptability of self-sampling HPV testing in cervical cancer screening: a population-based study in rural Yunnan, China.

Scientific reports
To evaluate the accuracy and acceptability of self-sampling samples for HPV testing for cervical cancer screening in rural Yunnan of China. In 2022, 3000 women aged 17-69 were recruited and provided self-sampling vaginal samples alongside provider-sa...

Development and performance of female breast cancer incidence risk prediction models: a systematic review and meta-analysis.

Annals of medicine
INTRODUCTION: Accurate breast cancer risk prediction is essential for early detection and personalized prevention strategies. While traditional models, such as Gail and Tyrer-Cuzick, are widely utilized, machine learning-based approaches may offer en...