CNN-Based Device-Agnostic Feature Extraction From ONH OCT Scans.

Journal: Translational vision science & technology
PMID:

Abstract

PURPOSE: Optical coherence tomography (OCT)-derived measurements of the optic nerve head (ONH) from different devices are not interchangeable. This poses challenges to patient follow-up and collaborative studies. Here, we present a device-agnostic method for the extraction of OCT biomarkers using artificial intelligence.

Authors

  • Sjoerd J Driessen
    Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Karin A van Garderen
    Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Danilo Andrade De Jesus
    Eye Image Analysis Group Rotterdam, Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Luisa Sanchez Brea
    Eye Image Analysis Group Rotterdam, Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • João Barbosa-Breda
    Research Group Ophthalmology, KU Leuven, Leuven, Belgium.
  • Bart Liefers
    Diagnostic Image Analysis Group, Department of Radiology, Radboud University Medical Center, Nijmegen, The Netherlands; Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: Bart.Liefers@radboudumc.nl.
  • Hans G Lemij
    Rotterdam Eye Hospital, Rotterdam, The Netherlands.
  • Doreen Nelson-Ayifah
    Department of Ophthalmology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
  • Angelina Ampong
    Department of Ophthalmology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
  • Pieter W M Bonnemaijer
    Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Alberta A H J Thiadens
    Department of Ophthalmology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Caroline C W Klaver
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands; Department of Ophthalmology, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Ophthalmology, Radboud University Medical Center, Nijmegen, The Netherlands; Institute for Molecular and Clinical Ophthalmology, Basel, Switzerland.