Deep learning-based acceleration of muscle water T2 mapping in patients with neuromuscular diseases by more than 50% - translating quantitative MRI from research to clinical routine.

Journal: PloS one
PMID: 40238781

Abstract

BACKGROUND: Quantitative muscle water T2 (T2w) mapping is regarded as a biomarker for disease activity and response to treatment in neuromuscular diseases (NMD). However, the implementation in clinical settings is limited due to long scanning times and low resolution. Using artificial intelligence (AI) to accelerate MR image acquisition offers a possible solution. Combining compressed sensing and parallel imaging with AI-based reconstruction, known as CSAI (SmartSpeed, Philips Healthcare), allows for the generation of high-quality, weighted MR images in a shorter scan time. However, CSAI has not yet been investigated for quantitative MRI. Therefore, in the present work we assessed the performance of CSAI acceleration for T2w mapping compared to standard acceleration with SENSE.

Authors

  • Joachim Schmitt
    Department of Diagnostic and Interventional Neuroradiology, School of Medicine and Health, TUM Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Dominik Weidlich
    Department of Diagnostic and Interventional Radiology, School of Medicine and Health, TUM Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Kilian Weiss
    Philips GmbH, Röntgenstrasse 22, 22335, Hamburg, Germany.
  • Jonathan Stelter
    Department of Diagnostic and Interventional Radiology, School of Medicine and Health, TUM Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Federica Montagnese
    Department of Neurology, Friedrich-Baur-Institute, LMU Munich, Munich, Germany.
  • Marcus Deschauer
    Department of Neurology, School of Medicine and Health, TUM Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany.
  • Benedikt Schoser
    Friedrich-Baur-Institute at the Department of Neurology, LMU University Hospital, LMU Munich, Ziemssenstr.1 80336 Munich, Germany.
  • Claus Zimmer
    Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Strasse 22, 81675 Munich, Germany.
  • Dimitrios C Karampinos
    Department of Radiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, Munich, Germany.
  • Jan S Kirschke
    Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.
  • Sarah Schlaeger
    Department of Diagnostic and Interventional Neuroradiology, School of Medicine, Technical University of Munich, Munich, Germany.

Keywords

External Resources

Popular Topics
Recent Journals