Current status, challenges, and prospects of artificial intelligence applications in wound repair theranostics.

Journal: Theranostics
PMID:

Abstract

Skin injuries caused by physical, pathological, and chemical factors not only compromise appearance and barrier function but can also lead to life-threatening microbial infections, posing significant challenges for patients and healthcare systems. Artificial intelligence (AI) technology has demonstrated substantial advantages in processing and analyzing image information. Recently, AI-based methods and algorithms, including machine learning, deep learning, and neural networks, have been extensively explored in wound care and research, providing effective clinical decision support for wound diagnosis, treatment, prognosis, and rehabilitation. However, challenges remain in achieving a closed-loop care system for the comprehensive application of AI in wound management, encompassing wound diagnosis, monitoring, and treatment. This review comprehensively summarizes recent advancements in AI applications in wound repair. Specifically, it discusses AI's role in injury type classification, wound measurement (including area and depth), wound tissue type classification, wound monitoring and prediction, and personalized treatment. Additionally, the review addresses the challenges and limitations AI faces in wound management. Finally, recommendations for the application of AI in wound repair are proposed, along with an outlook on future research directions, aiming to provide scientific evidence and technological support for further advancements in AI-driven wound repair theranostics.

Authors

  • Huazhen Liu
    School of Information & Electrical Engineering, Hebei University of Engineering, Handan 056038, China.
  • Wenbin Sun
    School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, People's Republic of China.
  • Weihuang Cai
    School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, People's Republic of China.
  • Kaidi Luo
    School of Medicine, Shanghai University, Shanghai, 200444, People's Republic of China.
  • Chunxiang Lu
    School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, People's Republic of China.
  • Aoxiang Jin
    School of Mechatronic Engineering and Automation, Shanghai University, Shanghai, People's Republic of China.
  • Jiantao Zhang
    Heilongjiang Key Laboratory for Laboratory Animals and Comparative Medicine, College of Veterinary Medicine, Harbin 150030, China.
  • Yuanyuan Liu
    College of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing 400065, China.