Multiple token rearrangement Transformer network with explicit superpixel constraint for segmentation of echocardiography.

Journal: Medical image analysis
PMID:

Abstract

Diagnostic cardiologists have considerable clinical demand for precise segmentation of echocardiography to diagnose cardiovascular disease. The paradox is that manual segmentation of echocardiography is a time-consuming and operator-dependent task. Computer-aided segmentation can reduce the workflow greatly. However, it is challenging to segment multi-type echocardiography, which is reflected in differential anatomic structures, artifacts, and blurred borderline. This study proposes the multiple token rearrangement Transformer network (MTRT-Net) embedded in three novel modules to address the corresponding three challenges. First, the depthwise deformable attention module can extract flexible features to adapt to anatomic structures of echocardiography with different ages and diseases. Second, the superpixel supervised module can cluster similar features and keep discriminative features away to make the segmentation regions tend to be an entire body. The artifacts have the influence in separating the complete internal region. Third, the atrous affinity aggregation module can integrate affinity features near the borderline to judge the blurred regions. Overall, the three modules rearrange the relationships of tokens and broaden the diversity of features. Besides, the explicit constraint brought by the superpixel supervised module enhances the performance of fitting ability. This study has 13747 echocardiography to train and test the MTRT-Net. Abundant experiments also validate the performance of MTRT-Net. Therefore, MTRT-Net can assist the diagnostician in segmenting the echocardiography precisely.

Authors

  • Wanli Ding
    Key Laboratory of Digital Signal and Image Processing of Guangdong Province, Department of Electronic Engineering, Shantou University, Shantou, Guangdong, China.
  • Heye Zhang
    School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, China.
  • Xiujian Liu
    School of Biomedical Engineering, Sun Yat-sen University, Shenzhen 518107, China.
  • Zhenxuan Zhang
    School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, China.
  • Shuxin Zhuang
    School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, Guangdong, China.
  • Zhifan Gao
    School of Biomedical Engineering, Sun Yat-sen University, Shenzhen, China.
  • Lin Xu
    Key Laboratory of Grain and Oil Processing and Food Safety of Sichuan Province, College of Food and Bioengineering, Xihua University Chengdu 610039 China xingyage1@163.com.