Semantic search helper: A tool based on the use of embeddings in multi-item questionnaires as a harmonization opportunity for merging large datasets - A feasibility study.

Journal: European psychiatry : the journal of the Association of European Psychiatrists
PMID:

Abstract

BACKGROUND: Recent advances in natural language processing (NLP), particularly in language processing methods, have opened new avenues in semantic data analysis. A promising application of NLP is data harmonization in questionnaire-based cohort studies, where it can be used as an additional method, specifically when only different instruments are available for one construct as well as for the evaluation of potentially new construct-constellations. The present article therefore explores embedding models' potential to detect opportunities for semantic harmonization.

Authors

  • Karl Gottfried
    Institute of Applied Medical Informatics, University Hospital Center Hamburg-Eppendorf, Hamburg, Germany.
  • Karina Janson
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Baden-Württemberg, Germany.
  • Nathalie E Holz
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Baden-Württemberg, Germany.
  • Olaf Reis
    Department of Child and Adolescent Psychiatry, Neurology, Psychosomatics and Psychotherapy, Rostock University Medical Centre, Rostock, Germany.
  • Johannes Kornhuber
    Clinic for Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nuremberg, Germany.
  • Anna Eichler
    Department of Child and Adolescent Mental Health, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Tobias Banaschewski
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159 Mannheim, Germany.
  • Frauke Nees
    Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, 68159 Mannheim, Germany; Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Square J5, Mannheim, Germany.