A Supervised Explainable Machine Learning Model for Perioperative Neurocognitive Disorder in Liver-Transplantation Patients and External Validation on the Medical Information Mart for Intensive Care IV Database: Retrospective Study.

Journal: Journal of medical Internet research
PMID:

Abstract

BACKGROUND: Patients undergoing liver transplantation (LT) are at risk of perioperative neurocognitive dysfunction (PND), which significantly affects the patients' prognosis.

Authors

  • Zhendong Ding
    Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Linan Zhang
    Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Yihan Zhang
    Department of Ophthalmology, Fudan Eye & ENT Hospital, Shanghai, China.
  • Jing Yang
    Beijing Novartis Pharma Co. Ltd., Beijing, China.
  • Yuheng Luo
    Institute of Animal Nutrition, Sichuan Agricultural University, Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Key Laboratory of Animal Disease-resistant Nutrition and Feed of China Ministry of Agriculture and Rural Affairs, Key Laboratory of Animal Disease-resistant Nutrition of Sichuan Province, Ya'an, 625014, China.
  • Mian Ge
    Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Weifeng Yao
    Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Ziqing Hei
    Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road, Guangzhou, 10630, Guangdong, People's Republic of China. heiziqing@sina.com.
  • Chaojin Chen
    Department of Anesthesiology, The Third Affiliated Hospital of Sun Yat-Sen University, No. 600 Tianhe Road, Guangzhou, 10630, Guangdong, People's Republic of China.