Improving spleen segmentation in ultrasound images using a hybrid deep learning framework.

Journal: Scientific reports
PMID:

Abstract

This paper introduces a novel method for spleen segmentation in ultrasound images, using a two-phase training approach. In the first phase, the SegFormerB0 network is trained to provide an initial segmentation. In the second phase, the network is further refined using the Pix2Pix structure, which enhances attention to details and corrects any erroneous or additional segments in the output. This hybrid method effectively combines the strengths of both SegFormer and Pix2Pix to produce highly accurate segmentation results. We have assembled the Spleenex dataset, consisting of 450 ultrasound images of the spleen, which is the first dataset of its kind in this field. Our method has been validated on this dataset, and the experimental results show that it outperforms existing state-of-the-art models. Specifically, our approach achieved a mean Intersection over Union (mIoU) of 94.17% and a mean Dice (mDice) score of 96.82%, surpassing models such as Splenomegaly Segmentation Network (SSNet), U-Net, and Variational autoencoder based methods. The proposed method also achieved a Mean Percentage Length Error (MPLE) of 3.64%, further demonstrating its accuracy. Furthermore, the proposed method has demonstrated strong performance even in the presence of noise in ultrasound images, highlighting its practical applicability in clinical environments.

Authors

  • Ali Karimi
    Department of Pharmaceutics, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Javad Seraj
    School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran.
  • Fatemeh Mirzadeh Sarcheshmeh
    School of Mechanical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
  • Kasra Fazli
    School of Electrical and Computer Engineering, College of Engineering, University of Tehran, Tehran, Iran.
  • Amirali Seraj
    Faculty of Electrical Engineering, Shahid Beheshti University, Tehran, Iran.
  • Parisa Eslami
    Department of Information Systems, University of Maryland, Baltimore County, Baltimore, USA.
  • Mohamadreza Khanmohamadi
    Applied Artificial Intelligence Laboratory, University of Tehran, Tehran, Iran.
  • Helia Sajjadian Moosavi
    Department of Computer Science, University of Toronto, Toronto, ON, Canada.
  • Hadi Ghattan Kashani
    Applied Artificial Intelligence Laboratory, University of Tehran, Tehran, Iran.
  • Abdoulreza Sajjadian Moosavi
    Imaging department, Golestan Radiology and Sonography Clinic, Tehran, Iran. a.sajjadianmoosavi@gmail.com.
  • Masoud Shariat Panahi
    School of Mechanical Engineering, College of Engineering, University of Tehran, Tehran, Iran.