Two-Layer Retrieval-Augmented Generation Framework for Low-Resource Medical Question Answering Using Reddit Data: Proof-of-Concept Study.

Journal: Journal of medical Internet research
PMID: 39761554

Abstract

BACKGROUND: The increasing use of social media to share lived and living experiences of substance use presents a unique opportunity to obtain information on side effects, use patterns, and opinions on novel psychoactive substances. However, due to the large volume of data, obtaining useful insights through natural language processing technologies such as large language models is challenging.

Authors

  • Sudeshna Das
    Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Yao Ge
    James Watt School of Engineering, University of Glasgow, Glasgow, G12 8QQ, UK.
  • Yuting Guo
    State Key Laboratory of Virtual Reality Technology and Systems, Beihang University, Beijing, China.
  • Swati Rajwal
    Department of Computer Science and Informatics, Emory University, Atlanta, GA, United States.
  • JaMor Hairston
    University of Alabama at Birmingham, Birmingham, Alabama, United States of America.
  • Jeanne Powell
    Department of Biomedical Informatics, School of Medicine, Emory University, Atlanta, GA, United States.
  • Drew Walker
    Department of Behavioral, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, United States.
  • Snigdha Peddireddy
    Department of Behavioral, Social & Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, GA, United States.
  • Sahithi Lakamana
    Department of Biomedical Informatics, School of Medicine, Emory University, Atlanta, GA, United States.
  • Selen Bozkurt
    Department of Biostatistics and Medical Informatics, Akdeniz University Faculty of Medinice, 48000 Antalya, Turkey.
  • Matthew Reyna
  • Reza Sameni
    Department of Biomedical Informatics, Emory University, Atlanta, GA 30322, USA.
  • Yunyu Xiao
    Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.
  • Sangmi Kim
    Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States.
  • Rasheeta Chandler
    Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States.
  • Natalie Hernandez
    Center for Maternal Health Equity, Morehouse School of Medicine, Atlanta, GA, United States.
  • Danielle Mowery
    Department of Biomedical Informatics, University of Utah, 421 Wakara Way, Salt Lake City, 84108 UT United States.
  • Rachel Wightman
    Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI, United States.
  • Jennifer Love
    Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
  • Anthony Spadaro
    Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, NJ, United States.
  • Jeanmarie Perrone
    Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia.
  • Abeed Sarker
    Department of Biomedical Informatics, School of Medicine, Emory University, Atlanta, GA, United States.

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