AIMC Topic: Proof of Concept Study
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Usability of machine learning algorithms based on electronic health records for the prediction of acute kidney injury and transition to acute kidney disease: A proof of concept study.
PloS one
Jul 1, 2025
BACKGROUND: Acute kidney injury (AKI) and acute kidney disease (AKD) are frequent complications of hospitalization, resulting in reduced outcomes and increased cost burden. However, these conditions are only sometimes recognized and promptly treated....
Microbiome and fragmentation pattern of blood cell-free DNA and fecal metagenome enhance colorectal cancer micro-dysbiosis and diagnosis analysis: a proof-of-concept study.
mSystems
Apr 29, 2025
Colorectal cancer (CRC) is the third most common cancer, and it can be prevented by performing early screening. As a hallmark of cancer, the human microbiome plays important roles in the occurrence and development of CRC. Recently, the blood microbio...
Transformer-based deep learning enables improved B-cell epitope prediction in parasitic pathogens: A proof-of-concept study on Fasciola hepatica.
PLoS neglected tropical diseases
Apr 29, 2025
BACKGROUND: The identification of B-cell epitopes (BCEs) is fundamental to advancing epitope-based vaccine design, therapeutic antibody development, and diagnostics, such as in neglected tropical diseases caused by parasitic pathogens. However, the s...
Generating Artificial Patients With Reliable Clinical Characteristics Using a Geometry-Based Variational Autoencoder: Proof-of-Concept Feasibility Study.
Journal of medical Internet research
Apr 17, 2025
BACKGROUND: Artificial patient technology could transform health care by accelerating diagnosis, treatment, and mapping clinical pathways. Deep learning methods for generating artificial data in health care include data augmentation by variational au...
Assessing Patient-Reported Satisfaction With Care and Documentation Time in Primary Care Through AI-Driven Automatic Clinical Note Generation: Protocol for a Proof-of-Concept Study.
JMIR research protocols
Apr 7, 2025
BACKGROUND: Relisten is an artificial intelligence (AI)-based software developed by Recog Analytics that improves patient care by facilitating more natural interactions between health care professionals and patients. This tool extracts relevant infor...
Machine Vision Augmentation to Detect Detrusor Overactivity in Overactive Bladder: A Frontier of Artificial Intelligence Application in Functional Urology-Proof of Concept Clinical Study.
Neurourology and urodynamics
Apr 1, 2025
INTRODUCTION: Overactive bladder (OAB) is a common urological condition with increasing prevalence, especially in an aging population. Diagnosing and treating OAB can be challenging. While urodynamic study (UDS) is useful to confirm involuntary detru...
Machine Learning Models predicting Decompensation in Cirrhosis.
Journal of gastrointestinal and liver diseases : JGLD
Mar 27, 2025
BACKGROUND AND AIMS: Decompensation of cirrhosis significantly decreases survival, thus, prevention of complications is paramount. We used machine learning techniques to identify parameters predicting decompensation.
Automated Identification of Stroke Thrombolysis Contraindications from Synthetic Clinical Notes: A Proof-of-Concept Study.
Cerebrovascular diseases extra
Mar 17, 2025
INTRODUCTION: Timely thrombolytic therapy improves outcomes in acute ischemic stroke. Manual chart review to screen for thrombolysis contraindications may be time-consuming and prone to errors. We developed and tested a large language model (LLM)-bas...
An artificial intelligence-informed proof of concept model for an ecological framework of healthy longevity forcing factors in the United States.
Current problems in cardiology
Mar 14, 2025
Unhealthy lifestyle behaviors are a doorway to downstream health consequences characterized by the following: 1) poor quality of life and diminished mobility; 2) increased likelihood of chronic disease risk factors and diagnoses; and, ultimately, 3) ...
Augmenting rehabilitation robotics with spinal cord neuromodulation: A proof of concept.
Science robotics
Mar 12, 2025
Rehabilitation robotics aims to promote activity-dependent reorganization of the nervous system. However, people with paralysis cannot generate sufficient activity during robot-assisted rehabilitation and, consequently, do not benefit from these ther...
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